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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f015d83c48be09c0c77abc3e7106853d9bc9bf886f8a0091bd6d6c0a29c7475' 
  AND token = 'bjjotyXB4IWpcMiAZ+ma5TNnwVT3ZahceWuDCHGp16g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}