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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b88b9521232736d91538c9bfec774f5818a67b8fcfdaf021fbd3b8fdc9b6c22e' 
  AND token = '9UM2GSik41JnV0YyJPAEqvOl4HSibGlOpeN+A4aw1Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}