SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3caeb9685ff0e02294ac319fb66ce3b71ebbf829d462e529cc4ffee07690768c' 
  AND token = 'hNRcVTScRsc31kG33UG/Cf56Jw01ct7VnGojVewGTa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}