SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8180e362b45dedca803a6c091f0a8062c544c922a349aae1efcd33d878bf74e1' 
  AND token = 'Q8pj9duOYPxTCIFg/59yrqX83ICvhj/Y4oh4ShRWzGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}