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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19ee8b1b926315f95b4797108d9bed69fa64aca82d8117c267be83db278f6717' 
  AND token = '61NUDKaAMAMp2PNKDNTFvaQuZR3WDh/yGQiMe1zI+qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}