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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d7d1d97aa23a5802812900e6d007ac04eea140803ef9fc10eaaf50d37837af4' 
  AND token = 'uCSDzJS6vk6pS+iB3gf2qzVKumVvSzBOXGr9fCeqFQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}