SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade45c501f721842e21f32666f1c5c3fd71fea6ae94dacddb4f8f38ae69e8bfc' 
  AND token = 'Eqi+GRoMduU3sTshvAT2LMiqrBWEo3PXtliBQwv9Avw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}