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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390e406d0f8e5be9d37894c7e1d37481135e4abf16124d0c40e2b05a15a254d1' 
  AND token = 'xY1Q8xc1pnkxW+WLChLM4H0cSCFk5O54mcr+aL3EMnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}