SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308cbf8ffde91158aaa5262c16db0c73c2a5d55d256aa958e201a847b0733eac' 
  AND token = 'ToEy5RTcTlrrcCjiTqZXH9SrhLoZJcSuLANYi/Dkh4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}