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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be02d1acf83f14010eb062ed78cb8c3b36aa642a13182c427a6ebc3476dd201' 
  AND token = 'XfHo3y6hX1VZoxwYsb8b7EBQe9l5uePVfgS7tjbROL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}