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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0349209362b74114c8222a59068f1ec2e16b734f1431bcf35c7994c87978f0a' 
  AND token = 'hhsI9PHSs/7i91e5VobVyo2WhGcZP0lC5ZYDtoTz7zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}