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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1e09f01a9c1235ff4050ba7eb43edeb72b5a891f5f23f76e4a1b76c05515e0' 
  AND token = 'QMk/Ho/LKM5Hd3qiMSVIRFl8lHo2CxNgkDhDzANQZ50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}