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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c65f2d2c25f12d254ded75bc265d68a25d3675373e27a6814b685978dfc674' 
  AND token = 'b8kmZp9w+5JWj4iob/etwN+Cjk7JI1SxFabi7vwW7JI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}