SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a075653609c9275d41078e972bb83aa83d5f5256bdb5bde1fcd9ce94b0a1c7e4' 
  AND token = '1TaOp889WFNILkVRxdi507xvHXDtbzudiEx0TUVpE34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}