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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b82d697e892318e48f02571fea2227a80844efa4d781a68ce9275a2958e66d5b' 
  AND token = 'pZiN31/tZYyYb3rmI/U83f0W6JzEaOiRpoB2OzaVYOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}