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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503881d8c9049e1c2647beab4ffbf7a82bf8ceab2f579713e40d5ba86879d498' 
  AND token = 'mTtu3680cucHlY9VPlLSWSc/dNAIHtOzxivgMCXHbL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}