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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5a1f514bbc1299db712e43009c76972da8a604ee30b1b75b98acc1fdf4eee06' 
  AND token = 'M2nvCy73gNoUEhGTYcRzaeEYoGSp3WFHGzFR4qYOQP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}