SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c9f052a38670644c23fd4c3f2611b8d14d8ee039a99b3cef9bb05eb495c743' 
  AND token = '/9qypgMmHwDFn77/NDGFsyAxC+psfshvbfmASwdF8s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}