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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643bf19ab5e6bae3fd1a7b2b555ae3401cdfa3f05e1a59a6d3c83f9b3096c195' 
  AND token = '+gFwbE638u1e4S/D8oNEinjwHj6b91ObBf2Gje5FK8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}