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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178da4c97f6b235efbd9743dc72a3392baf4721bdeb24d0404f09de1cb1888e3' 
  AND token = '4IFSoFOO4Usyn3AfzWin1Tvu/PrKBFB2b/STSU+0fuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}