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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f169bdf976b457559bee12c39a4e32175e812540a29b949726aa8381075f2fc7' 
  AND token = '03FtQ/S3PNx2m4vM8i152/uRwuDHcy47P/PQXwaMKCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}