SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b22d441c705ad99a055b22ca63e63413688f5085e29a11206c349a270ea1f0c' 
  AND token = 'V2uBm4obsMu5UCB24DM9lZNmqUxVIIqRC1ltt6Cw1ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}