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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95c82f48962f1da3cca00f3722e22e9b8dd5cba671508d796e283883bebe7c1' 
  AND token = 'DDYWegSXAYI1DhZ0dmSCFiRRj5HUhtUmIMnoVGyh2uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}