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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63c65493b83d7fe3480fa24d9c4e3f97f6648f0f92c32e160df710cf58412713' 
  AND token = 'Dz1y2C6UioaV6VaZ32mKCCVxmwcn+dboLTMDYGa0LUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}