SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c937a697f2e28d2501e0b8fd9ade8b22d410e1ced1f7464530d73b3de0be400f' 
  AND token = 'ksvcQMAXf21i2I5hXQAM9Kd4M9xCxDYmQykVEVkxmHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}