SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382c3ab038dc2af2f8dd14123e9466d325646c96007f8022998d1136ed458599' 
  AND token = 'xcpZhIVA3Bi+EO/qrXra+zrLSKw5LqXyQBnXe787zVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}