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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37431db6189a4fd06e5e64a5e6cd6d46cd0554b3c4b304b704811fe83f71b845' 
  AND token = 'u5y5plU2PUDuSIG3dYHSRod2K6bcRTKyBm9eQMxNTkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}