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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd40cda8d3ee1e259f855a262c96a654780c7ce703e362a7c77b7c61225a8e297' 
  AND token = 'MbGE+hbQR556l3YGTBjGonRDe0xhOa4PG9xvA5h1eNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}