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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2165e7d158a5227cb85c84463a4685fa17d53388b1683e729308ac8ec4c55a' 
  AND token = 'QT+Rdvdv7UkEfckxqZic7bhYUgZAfN5D75UwIXY37lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}