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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257a636d014b59c9098728d3c1b5eea76bf18b57c8d319118c17cb6372ebfac7' 
  AND token = 'kLm3Ad2+z5TjfUn9CKzAL4p2KxJHgy80GBanUHIEfcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}