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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2f891a24b9798460c2d4022b7684490d2d6c152c7fe86219e1195ed5143001' 
  AND token = 'xKe1+eiTLQXPgbkIv3ndLLBSNtVALJBG4HgY/8ggCWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}