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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f46d75c7049337182dbc0f886302e88a356bed0f0303d6d9f948d4988e64b36' 
  AND token = 'hrhsh9ux9PaKIHozinUh3WSYRreRbuznECRef5yOzwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}