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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2f4d58dc48e32d3211b647caf15c9208c618e7634a101a11bc051e0adfc823c' 
  AND token = 'BndWUUy789nfjoz9b/hCLneLN/G7YogMQg5KZko4D84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}