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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a376e0fe1bc02a76e065b51a42da2f543b92522b913ddd82026c7d25de55e82e' 
  AND token = 'CwEyULBp/cYzHXoneBNSUPjPsFEp3rUmLxF2h/o6Zbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}