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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f3e429790bda47f1257c6d3e254f21c6148eb6bcc313b1e1d7162f50270f03' 
  AND token = 'C3LEJuZHJHGTAiln13zeWZxmqa5aUrd/GYNQ9wI0PYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}