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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2499953e569dd8a8e6eb868d0719b5d2ace04e34915ab536d1a79162de038d98' 
  AND token = 'ya/NDQ1dyhiEHM5z5/6M47L+VmfvzE+17daLwLTJoDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}