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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b73015d132129a7cb607b72b91045aa2135eaa9bed987b439fd922abf06e56' 
  AND token = 'iRiUR6b9OHvuww6vIWI0xmmkLTA1kbsYqhz83ZoctuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}