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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5901dd70af78d08345da29d26e3f29ed5cf1f45d1c5d02a26de715fc2b7de9b5' 
  AND token = 'q8CTgB1eXNUOFfYiyzbYRlItyvVIhuEmEnJiupOKb60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}