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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44fe3b340c7f91f0c2bbd9fea9314ee5096e8c61a9c0da1bff67c309504d5649' 
  AND token = 'Yu3qe7g+6yx5ZuYQjYvknrvI/GRHRZOR5n2anFHHKqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}