SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000593ff71d51c776b0fca8422bcf1ad1c5e4c01728260ce49d21cd961b5b4be' 
  AND token = 'AEJPNzIPjChnu5dINolq4kTYwHUOrloi27fv+/pnNqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}