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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a8c36752001f65d9e558cafe1265a0fd7e75915e7249ffeb1d821fae7b0b15' 
  AND token = 'Tptzzkq/I5HMRqPAqk2xt5Amlby5tuc7bEFGiUjVBdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}