SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756acb49a052eb23e548bbaf52041507d02b1d12ba9155d3235e4d7506478f3f' 
  AND token = 'dNWcDQ+9FUq+sYFNR/ZrrX4E0nbax+b85uy4oAzGa6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}