SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a927f36459951b152732149e1247054392605832c41f4903554431d1b6222c5' 
  AND token = 'RUB4LivN8j2Ol0LItJNtiVbOrj0Anr9IEWEUo28aoKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}