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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b315cf22c61ee5f6625d73fd05ff137cb0fa377a583aa4fe800b64e9f1ab427' 
  AND token = 'bte7j95GbWZq0g5GTLOOfEZ2bK/GvTOzQznnjDX+5Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}