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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a51191c349b2adfe8b180897440d56a69a796618f40143b2e500a5b9b6beac' 
  AND token = '+MK2CCJLuSr26oKpMi1MR1rbTEeC9sIzUlcyubEJpNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}