SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408ed51cdde17f4d6d7ea05e10d5be6f481dfec4bcf218dd5f4fb06b8a5c33a2' 
  AND token = 'xB2GHgtOYPPAR+X+tU2P+JcoflrICUy+O/rQ4aRt3Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}