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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6210be5a59a76f19fdfd89bb25aa4b549739dcfe08e3210c8867f82a8af0d8' 
  AND token = '/yGlsQcsKSYg8XL4HLRX/LtrNV4QCfdiUij0yQQNGdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}