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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253f90b2135d2193dd6ed4560fd9a08cfd907cd4c5ee2633bd8a76fb05497dc9' 
  AND token = 'ZzPfdfTPcijkhqrP2vw8S1uFfOQMc55vZlGeuJv4yUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}