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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d4814d21b98ef7fd64dca46cfd72254f5b4390ff81634093e09e2ae5777ecb' 
  AND token = 'QZNpnCo4O7mkq4ttdIIdMqysJJXZK9WjnB1yCCwUuJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}