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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '555b4b2633e832700cce3a7e294a8cabde071097777a81834291da22e1967e3d' 
  AND token = '+YEJLkQQ2Ykt/jtvz6zwT4HDhAu2AJv7LZXLC7ezAic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}